A Meta Analysis Is Best Described as
The first five principal components in GS were fitted to account for population stratification. The Münster cohort is described in Wray et al.
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The meta package contains a function called metareg which allows us to conduct a meta-regressionThe metareg function only requires a meta meta-analysis object and the name of a covariate as input.
. 9 and although this cohort was not part of their meta-analysis it was used for out of sample prediction using polygenic risk scores. By combining the sample estimates the meta-analysis reduced the evidence to a manageable quantity. The best thresholds for the meta-analysis PRS PP.
The interpretation of a forest plot has been described in a previous question2. In this example we will use our mgen meta-analysis object again which is based on the ThirdWave data set see Chapter 421Using meta-regression we want to. The figure shows the forest plot for the meta-analysis.
The objective of the analysis was to assess the effectiveness of primary prophylaxis with PREVYMIS among adults undergoing alloHCT using systematic literature review and meta-analysis of data from. In summary the Münster cohort is a clinically.
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